Not all sufferers with CLL require therapy. Irrespective of all latest advances, the iwCLL even now recommends watchful observation for individuals with asymptomatic disease.86 This recommendation relies on at the least two randomized trials comparing observation to possibly chlorambucil monotherapy or fludarabine, cyclophosphamide and rituximab (FCR).103,104 Both trials concluded that https://oliverd197ajr5.bmswiki.com/user