Epidural clonidine applied as an adjunct to nearby anesthetics has three distinctive mechanisms of action. Initially, the stimulation of alpha-two-receptors in the dorsal horn lessens discomfort transmission. Secondly, clonidine can cause local vasoconstriction that boundaries vascular elimination of local epidural anesthetics. Serious Allergic Reactions. Clonidine may lead to allergic https://isaacm146kga4.wikipowell.com/user